• Barrett House constructed.
• Estill Hall constructed.
• Parkhill House constructed.
• Randel House constructed.
• Spivey House constructed.
• Vick House constructed.
• January 9
  • Epsilon Zeta chapter of Delta Tau Delta fraternity founded.
• January 20
  • Zeta Mu chapter of Alpha Tau Omega fraternity founded.

• Allen House constructed.
• Aydelotte House constructed.
• Gidley House constructed.
• Gintz Apartments constructed.
• Hathorn House constructed.
• McCray House constructed.
• Smith Hall constructed.
• February 4
  • Epsilon Pi chapter of Pi Kappa Alpha fraternity founded.
• February 11
  • Epsilon Psi chapter of Sigma Chi fraternity founded.

• Kirkley Hall constructed.
• White Hall constructed.
• Woods Building constructed.
• Texas Eta chapter of Sigma Phi Epsilon fraternity founded.

• Lowman Student Center constructed.

• Kats for Christ Student Center constructed.
• Recital Hall constructed.
• Arleigh Templeton begins tenure as president until 1970.
• Enrollment exceeds 5,000.

• Colony Apartments constructed.
• Horticulture Center Lab constructed.
• Sigma Theta chapter of Chi Omega fraternity founded.
• April 13
  • Sam Houston State Teachers College becomes Sam Houston State College (until 1969).

• Academic Building One constructed.

• Art Building B constructed.
• Gresham Library constructed.
• Smith-Hutson Business Administration Building constructed.

• Abattoir Building constructed.
• Agriculture Center Arena constructed.
• Dairy Buildings constructed.
• Farm Power Machinery Building constructed.
• Feed Formulation Building constructed.
• Horse Management Building constructed.
• Layer and Breeder Building constructed.
• Poultry Laboratory constructed.
• Swine Laboratory constructed.
• Tractor Laboratory constructed.
• University Health Center constructed.
• Sam Houston State College becomes Sam Houston State University.