Adams House is located at the intersection of Avenue I and 20th Street on the south-central side of campus. In the Residence Life naming system, Adams and the surrounding small houses were classified as "Four Central" and later "The Valley."
The building has had many occupants as evidenced on older maps: it was at one time the former home of the Texas Eta chapter of the Sigma Phi Epsilon fraternity and then for many years the offices of the Housing and Food Services department. It wasn't until the 1990s that the building again became student housing and regularly appeared in print with Adams' name (probably once Adams Hall was demolished).
Residence Life announced in October 2005 that the house would be converted to offices beginning in January 2006 so that the Frels and Wilson buildings could be vacated in preparation for their demolition. The Office of Research and Special Programs moved to the building in Fall 2006.